Sec Form 13D Filing - BIOS Fund I LP filing for - 2025-05-27

Insider filing report for Changes in Beneficial Ownership

  • Schedule 13G & 13D forms are used to report a party's ownership of stock which exceeds 5% of a company's total stock issue.
  • Schedule 13G is a shorter version of Schedule 13D with fewer reporting requirements.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
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If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of shares of common stock, par value $0.000001 per share ("Shares") directly held by Bios Fund I, LP ("Bios Fund I"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Fund I QP, LP ("Bios Fund I QP"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 300,143 Shares, and (ii) 8,068 Shares issuable upon the exercise of warrants, directly held by Bios Fund II, LP ("Bios Fund II"). Percentage based on 19,627,728 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 8,068 Shares issuable upon the exercise of warrants held by Bios Fund II.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 980,433 Shares, and (ii) 26,355 Shares issuable upon the exercise of warrants, directly held by Bios Fund II QP, LP ("Bios Fund II QP"). Percentage based on 19,646,015 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 26,355 Shares issuable upon the exercise of warrants held by Bios Fund II QP.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 131,248 Shares, and (ii) 3,528 Shares issuable upon the exercise of warrants, directly held by Bios Fund II NT, LP ("Bios Fund II NT"). Percentage based on 19,623,188 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 3,528 Shares issuable upon the exercise of warrants held by Bios Fund II NT.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Fund III, LP ("Bios Fund III"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Fund III QP, LP ("Bios Fund III QP"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Fund III NT, LP ("Bios Fund III NT"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 84,971 Shares, and (ii) 31,884 Shares issuable upon the exercise of stock options, directly held by BP Directors, LP ("BP Directors"). Percentage based on 19,651,544 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 31,884 Shares issuable upon the exercise of stock options held by BP Directors.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Actuate Co-Invest I, LP ("Bios Actuate Co-Invest I"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Actuate Co-Invest II, LP ("Bios Actuate Co-Invest II"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Actuate Co-Invest III, LP ("Bios Actuate Co-Invest III"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios Clinical Opportunity Fund, LP ("Bios Clinical Opportunity Fund"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of Shares directly held by Bios 2024 Co-Invest, LP ("Bios 2024 Co-Invest"). Percentage based on 19,619,660 outstanding Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP and (iii) 84,917 Shares directly held by BP Directors, in each case (i-iii), as of the date hereof, and (iv) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors. Bios Equity Partners, LP ("Bios Equity I") is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. In its capacity as the general partner of these entities, Bios Equity I may be deemed to have shared voting and/or dispositive power with respect to securities directly held by these entities. Percentage based on 19,651,544 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 31,884 Shares issuable upon the exercise of stock options held by BP Directors.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 300,143 Shares directly held by Bios Fund II, (ii) 980,433 Shares directly held by Bios Fund II QP, (iii) 131,248 Shares directly held by Bios Fund II NT, (iv) 300,749 Shares directly held by Bios Actuate Co-Invest I, in each case (i-iv), as of the date hereof, (v) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (vi) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (vii) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (v-vii), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity Partners II, LP ("Bios Equity II") is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. In its capacity as the general partner of these entities, Bios Equity II may be deemed to have shared voting and/or dispositive power with respect to Shares directly or indirectly held by these entities. Percentage based on 19,657,611 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 383,791 outstanding Shares directly held by Bios Fund III, (ii) 2,506,667 outstanding Shares directly held by Bios Fund III QP, (iii) 404,814 outstanding Shares directly held by Bios Fund III NT, (iv) 2,094,650 outstanding Shares directly held by held by Bios Actuate Co-Invest II and (v) 573,394 outstanding Shares directly held by held by Bios Actuate Co-Invest III, in each case, as of the date hereof. Bios Equity Partners III, LP ("Bios Equity III") is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. In its capacity as the general partner of these entities, Bios Equity III may be deemed to have shared voting and/or dispositive power with respect to securities directly held by these entities. Percentage based on 19,619,660 Shares outstanding as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 1,259,427 Shares directly held by Bios Clinical Opportunity Fund and (ii) 125,000 Shares directly held by Bios 2024 Co-Invest, in each case, as of the date hereof. Bios Equity COF, LP ("Bios Equity COF") is the general partner of Bios Clinical Opportunity Fund and Bios 2024 Co-Invest. In its capacity as the general partner of these entities, Bios Equity COF may be deemed to have shared voting and/or dispositive power with respect to securities directly held by these entities. Percentage based on 19,619,660 Shares outstanding as reported in the Form 10-Q filed by the Issuer on May 15, 2025.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP, (iii) 84,917 Shares directly held by BP Directors (iv) 300,143 Shares directly held by Bios Fund II, (v) 980,433 Shares directly held by Bios Fund II QP, (vi) 131,248 Shares directly held by Bios Fund II NT, (vii) 300,749 Shares directly held by Bios Actuate Co-Invest I, (viii) 383,791 Shares directly held by Bios Fund III, (ix) 2,506,667 Shares directly held by Bios Fund III QP, (x) 404,814 Shares directly held by Bios Fund III NT, (xi) 2,094,650 Shares directly held by Bios Actuate Co-Invest II, (xii) 573,394 Shares directly held by Bios Actuate Co-Invest III, in each case (i-xii), as of the date hereof, (xiii) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors, (xiv) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (xv) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (xvi) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (xiii-xvi), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity I is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. Bios Equity II is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. Bios Equity III is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. Cavu Management, LP ("Cavu Management") is a general partner of Bios Equity I, Bios Equity II and Bios Equity III. In its capacity as a general partner of Bios Equity I, Bios Equity II and Bios Equity III, Cavu Management may be deemed to have shared voting and/or dispositive power with respect to securities directly held by Bios Fund I, Bios Fund I QP, BP Directors, Bios Fund II, Bios Fund II QP, Bios Fund II NT, Bios Actuate Co-Invest I, Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III (collectively, the "Bios Equity Entities"). Percentage based on 19,689,495 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT plus (iii) 31,884 Shares issuable upon exercise of stock options held by BP Directors.


SCHEDULE 13D



Com ment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP, (iii) 84,917 Shares directly held by BP Directors (iv) 300,143 Shares directly held by Bios Fund II, (v) 980,433 Shares directly held by Bios Fund II QP, (vi) 131,248 Shares directly held by Bios Fund II NT, (vii) 300,749 Shares directly held by Bios Actuate Co-Invest I, (viii) 383,791 Shares directly held by Bios Fund III, (ix) 2,506,667 Shares directly held by Bios Fund III QP, (x) 404,814 Shares directly held by Bios Fund III NT, (xi) 2,094,650 Shares directly held by Bios Actuate Co-Invest II, (xii) 573,394 Shares directly held by Bios Actuate Co-Invest III, (xiii) 1,259,427 Shares directly held by Bios Clinical Opportunity Fund, (xiv) 125,000 Shares directly held by Bios 2024 Co-Invest, in each case (i-xiv), as of the date hereof, (xv) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors, (xvi) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (xvii) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (xviii) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (xv-xviii), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity I is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. Bios Equity II is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. Bios Equity III is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. Bios Equity COF is the general partner of Bios Clinical Opportunity Fund and Bios 2024 Co-Invest. Bios Capital Management, LP ("Bios Management") is a general partner of Bios Equity I, Bios Equity II, Bios Equity III and Bios Equity COF. In its capacity as a general partner of Bios Equity I, Bios Equity II, Bios Equity III and Bios Equity COF Bios Management may be deemed to have shared voting and/or dispositive power with respect to securities directly held by the Bios Equity Entities. Percentage based on 19,689,495 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT plus (iii) 31,884 Shares issuable upon exercise of stock options held by BP Directors.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP, (iii) 84,917 Shares directly held by BP Directors (iv) 300,143 Shares directly held by Bios Fund II, (v) 980,433 Shares directly held by Bios Fund II QP, (vi) 131,248 Shares directly held by Bios Fund II NT, (vii) 300,749 Shares directly held by Bios Actuate Co-Invest I, (viii) 383,791 Shares directly held by Bios Fund III, (ix) 2,506,667 Shares directly held by Bios Fund III QP, (x) 404,814 Shares directly held by Bios Fund III NT, (xi) 2,094,650 Shares directly held by Bios Actuate Co-Invest II, (xii) 573,394 Shares directly held by Bios Actuate Co-Invest III, in each case (i-xii), as of the date hereof, (xiii) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors, (xiv) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (xv) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (xvi) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (xiii-xvi), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity I is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. Bios Equity II is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. Bios Equity III is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. Cavu Management is a general partner of Bios Equity I, Bios Equity II and Bios Equity III. Cavu Advisors, LLC ("Cavu Advisors") is the general partner of Cavu Management, and therefore may be deemed to have shared voting and/or dispositive power with respect to securities directly held by the Bios Equity Entities. Percentage based on 19,689,495 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT plus (iii) 31,884 Shares issuable upon exercise of stock options held by BP Directors.


SCHEDULE 13D



Comment for Type of Reporting Person:
Shared voting and dispositive power consists of (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP, (iii) 84,917 Shares directly held by BP Directors (iv) 300,143 Shares directly held by Bios Fund II, (v) 980,433 Shares directly held by Bios Fund II QP, (vi) 131,248 Shares directly held by Bios Fund II NT, (vii) 300,749 Shares directly held by Bios Actuate Co-Invest I, (viii) 383,791 Shares directly held by Bios Fund III, (ix) 2,506,667 Shares directly held by Bios Fund III QP, (x) 404,814 Shares directly held by Bios Fund III NT, (xi) 2,094,650 Shares directly held by Bios Actuate Co-Invest II, (xii) 573,394 Shares directly held by Bios Actuate Co-Invest III, (xiii) 1,259,427 Shares directly held by Bios Clinical Opportunity Fund, (xiv) 125,000 Shares directly held by Bios 2024 Co-Invest, in each case (i-xiv), as of the date hereof, (xv) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors, (xvi) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (xvii) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (xviii) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (xv-xviii), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity I is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. Bios Equity II is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. Bios Equity III is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. Bios Equity COF is the general partner of Bios Clinical Opportunity Fund and Bios 2024 Co-Invest. Bios Management is a general partner of Bios Equity I, Bios Equity II, Bios Equity III and Bios Equity COF. Bios Advisors GP, LLC ("Bios Advisors") is the general partner of Bios Management, and therefore, may be deemed to have shared voting and/or dispositive power with respect to securities directly held by the Bios Equity Entities. Percentage based on 19,689,495 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT plus (iii) 31,884 Shares issuable upon exercise of stock options held by BP Directors.


SCHEDULE 13D



Comment for Type of Reporting Person:
Sole voting and dispositive power consists of Shares directly held by Circle K, Invesco, LP ("Circle K"), over which Mr. Kreis has sole voting and investment control. Circle K is wholly owned by Mr. Kreis. Shared voting and dispositive power consists of (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP, (iii) 84,917 Shares directly held by BP Directors (iv) 300,143 Shares directly held by Bios Fund II, (v) 980,433 Shares directly held by Bios Fund II QP, (vi) 131,248 Shares directly held by Bios Fund II NT, (vii) 300,749 Shares directly held by Bios Actuate Co-Invest I, (viii) 383,791 Shares directly held by Bios Fund III, (ix) 2,506,667 Shares directly held by Bios Fund III QP, (x) 404,814 Shares directly held by Bios Fund III NT, (xi) 2,094,650 Shares directly held by Bios Actuate Co-Invest II, (xii) 573,394 Shares directly held by Bios Actuate Co-Invest III, in each case (i-xii), as of the date hereof, (xiii) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors, (xiv) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (xv) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (xvi) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (xiii-xvi), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity I is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. Bios Equity II is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. Bios Equity III is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. Cavu Management is a general partner of Bios Equity I, Bios Equity II and Bios Equity III. Cavu Advisors, an entity controlled by Mr. Kreis, is the general partner of Cavu Management. As the manager of Cavu Advisors, Mr. Kreis may be deemed to have shared voting and/or dispositive power with respect to securities directly held by the Bios Equity Entities. Percentage based on 19,689,495 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT plus (iii) 31,884 Shares issuable upon exercise of stock options held by BP Directors.


SCHEDULE 13D



Comment for Type of Reporting Person:
Excludes (i) 8,056 Shares directly held by KF Legacy Trust U/A/D December 7, 2016, which has an independent trustee, and (ii) 8,056 Shares directly held by KF Legacy Trust U/A/D December 7, 2016, which has an independent trustee. Dr. Fletcher disclaims beneficial ownership of the shares held by each of the KF Legacy Trust U/A/D December 7, 2016 and the MF Legacy Trust U/A/D December 7, 2016, which are trusts for the benefit of his children, other than to the extent he may have a pecuniary interest therein. Sole voting and dispositive power consists of 60,973 Shares directly held by Dr. Fletcher. Shared voting and dispositive power consists of (i) 525,797 Shares directly held by Bios Fund I, (ii) 307,538 Shares directly held by Bios Fund I QP, (iii) 84,917 Shares directly held by BP Directors (iv) 300,143 Shares directly held by Bios Fund II, (v) 980,433 Shares directly held by Bios Fund II QP, (vi) 131,248 Shares directly held by Bios Fund II NT, (vii) 300,749 Shares directly held by Bios Actuate Co-Invest I, (viii) 383,791 Shares directly held by Bios Fund III, (ix) 2,506,667 Shares directly held by Bios Fund III QP, (x) 404,814 Shares directly held by Bios Fund III NT, (xi) 2,094,650 Shares directly held by Bios Actuate Co-Invest II, (xii) 573,394 Shares directly held by Bios Actuate Co-Invest III, (xiii) 1,259,427 Shares directly held by Bios Clinical Opportunity Fund, (xiv) 125,000 Shares directly held by Bios 2024 Co-Invest, in each case (i-xiv), as of the date hereof, (xv) 31,884 Shares issuable upon exercise of stock options, directly held by BP Directors, (xvi) 8,068 Shares issuable upon exercise of warrants directly held by Bios Fund II, (xvii) 26,355 Shares issuable upon exercise of warrants directly held by Bios Fund II QP and (xviii) 3,528 Shares issuable upon exercise of warrants directly held by Bios Fund II NT, in each case (xv-xviii), which are exercisable or will be immediately exercisable within 60 days of the date hereof. Bios Equity I is the general partner of Bios Fund I, Bios Fund I QP and BP Directors. Bios Equity II is the general partner of Bios Fund II, Bios Fund II QP, Bios Fund II NT and Bios Actuate Co-Invest I. Bios Equity III is the general partner of Bios Fund III, Bios Fund III QP, Bios Fund III NT, Bios Actuate Co-Invest II and Bios Actuate Co-Invest III. Bios Equity COF is the general partner of Bios Clinical Opportunity Fund and Bios 2024 Co-Invest. Bios Management is a general partner of Bios Equity I, Bios Equity II, Bios Equity III and Bios Equity COF. Bios Advisors, an entity controlled by Dr. Fletcher, is the general partner of Bios Management. As the manager of Bios Advisors, Dr. Fletcher may be deemed to have shared voting and/or dispositive power with respect to securities directly held by the Bios Equity Entities. Percentage based on 19,689,495 outstanding Shares, including (i) 19,619,660 Shares as reported in the Form 10-Q filed by the Issuer on May 15, 2025 plus (ii) 37,951 Shares issuable upon the exercise of warrants collectively by Bios Fund II, Bios Fund II QP, and Bios Fund II NT plus (iii) 31,884 Shares issuable upon exercise of stock options held by BP Directors.


SCHEDULE 13D

 
BIOS FUND I, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND I QP, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND II, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND II QP, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND II NT, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND III, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND III QP, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS FUND III NT, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BP DIRECTORS, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS ACTUATE CO-INVEST I, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS ACTUATE CO-INVEST II, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS ACTUATE CO-INVEST III, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS CLINICAL OPPORTUNITY FUND, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS 2024 CO-INVEST, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS EQUITY PARTNERS, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS EQUITY PARTNERS II, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS EQUITY PARTNERS III, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS EQUITY COF, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
CAVU MANAGEMENT, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS CAPITAL MANAGEMENT, LP
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
CAVU ADVISORS, LLC
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
BIOS ADVISORS GP, LLC
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
LESLIE W. KREIS
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
 
AARON G.L. FLETCHER
 
Signature:John Fucci
Name/Title:Attorney-in-Fact
Date:05/27/2025
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