Sec Form 4 Filing - Blomquist Denise L. @ Medtronic plc - 2025-07-28

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Blomquist Denise L. 2. Issuer Name and Ticker or Trading Symbol Medtronic plc [ MDT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Chief Accounting Officer (Last) (First) (Middle) 710 MEDTRONIC PARKWAY 3. Date of Earliest Transaction (MM/DD/YY) 07/28/2025 (Street) MINNEAPOLIS, MN55432 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 07/28/2025 A 2,202 ( 1 ) A $ 0 12,425 ( 2 ) D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Performance Share Units ( 3 ) 07/28/2025 A 2,202 ( 4 ) ( 4 ) Performance Share Unit 2,202 ( 5 ) $ 0 2,202 D Stock Option (Right to Buy) $ 91.97 07/28/2025 A 1,278 ( 6 ) 07/28/2035 Ordinary Shares 1,278 $ 0 1,278 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Blomquist Denise L. 710 MEDTRONIC PARKWAY MINNEAPOLIS, MN55432 Chief Accounting Officer Signatures /s/ Patricia Walesiewicz, attorney-in-fact 07/30/2025 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Represents restricted stock units that vest 100% on the third anniversary of the date of grant. ( 2 )Includes 52 shares acquired through dividend reinvestment and 28 shares acquired under Medtronic's Employee Stock Ownership Plan since the last report filed by the reporting person. ( 3 )Each performance share unit represents a contingent right to receive one share of Medtronic common stock. ( 4 )Represents performance share units for which certain performance conditions will have been satisfied on April 28, 2028. ( 5 )The number of shares to be issued in connection with the performance share units ("PSUs") will vary depending on the level of certain performance metrics achieved over a three (3) year performance period. If target performance metrics are achieved, 2,202 shares will be issued. If maximum performance metrics are achieved, 4,404 shares will be issued. If minimum performance metrics are not met, such PSUs may vest at 0 shares. ( 6 )These options become exercisable at the rate of 25% of the shares granted per year beginning on the first anniversary of grant.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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