Sec Form 3 Filing - Lowery Frederick M. @ THERMO FISHER SCIENTIFIC INC. - 2024-04-23

FORM 3 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person Lowery Frederick M. 2. Issuer Name and Ticker or Trading Symbol THERMO FISHER SCIENTIFIC INC. [ TMO] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner X __ Officer (give title below) _____ Other (specify below) Executive Vice President (Last) (First) (Middle) 168 THIRD AVENUE 3. Date of Earliest Transaction (MM/DD/YY) 04/23/2024 (Street) WALTHAM, MA02451 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) __ X __ Form filed by One Reporting Person _____ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 11,186.3414 D Common Stock 5.032 I by Limited Liability Company ( 1 ) Common Stock 1,140.099 I by 401K

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exerci sable Expiration Date Title Amount or Number of Shares Stock Option (Right to Buy) $ 210.68 ( 2 ) 02/27/2025 Common Stock 18,300 D Stock Option (Right to Buy) $ 253.99 ( 3 ) 02/26/2026 Common Stock 13,825 D Stock Option (Right to Buy) $ 309.63 ( 4 ) 02/25/2027 Common Stock 12,675 D Stock Option (Right to Buy) $ 514.76 ( 5 ) 11/05/2027 Common Stock 3,870 D Stock Option (Right to Buy) $ 418.32 03/09/2024 09/09/2027 Common Stock 14,300 D Stock Option (Right to Buy) $ 458.81 ( 6 ) 02/23/2028 Common Stock 10,980 D Stock Option (Right to Buy) $ 528.58 ( 7 ) 02/23/2030 Common Stock 9,293 D Stock Option (Right to Buy) $ 536.7 ( 8 ) 09/06/2031 Common Stock 1,482 D Stock Option (Right to Buy) $ 548.4 ( 9 ) 02/22/2031 Common Stock 8,564 D Stock Option (Right to Buy) $ 552.85 ( 10 ) 02/21/2032 Common Stock 9,644 D

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Lowery Frederick M. 168 THIRD AVENUE WALTHAM, MA02451 Executive Vice President Signatures /s/ Melodie T. Morin, Attorney-in-Fact for Frederick M. Lowery 05/02/2024 Signature of Reporting Person Date

Explanation of Responses:

( 1 )The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein. ( 2 )The options vested in four equal installments on February 27, 2019, 2020, 2021, and 2022. ( 3 )The options vested in four equal installments on February 26, 2020, 2021, 2022, and 2023. ( 4 )The options vested in four equal installments on February 25, 2021, 2022, 2023, and 2024. ( 5 )The options vest in four equal annual installments. Three-quarters of the options vested on November 5, 2021, 2022, and 2023. The remaining one-quarter will vest on November 5, 2024. ( 6 )The options vest in four equal annual installments. Three-quarters of the options vested on February 23, 2022, 2023, and 2024. The remaining one-quarter will vest on February 23, 2025. ( 7 )The options vest in four equal annual installments. Two-quarters of the shares vested on February 28, 2023 and 2024, and the remaining two-quarters will vest on February 28, 2025 and 2026. ( 8 )The options vest in four equal annual installments on September 6, 2024, 2025, 2026, and 2027. ( 9 )The options vest in four equal annual installments. One-quarter of the shares vested on February 28, 2024, and the remaining three-quarters will vest on February 28, 2025, 2026 and 2027. ( 10 )The options vest in four equal annual installments on February 28, 2025, 2026, 2027 and 2028.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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